The Journal of Critical Care has published our initial evaluation of fractal exponents (the scaling coefficients from detrended fluctuation analysis) of heart rate variability in early sepsis and septic shock. In this study, we found that loss of fractal complexity in the time between successive heart beats was associated with poor response to initial resuscitation among patients arriving in the ICU with life-threatening infection.
    
Samuel Brown—physician leader, medical researcher, and cultural historian—is Professor of Medicine at Intermountain Medical Center/University of Utah Trained at Harvard College and Harvard Medical School, Dr. Brown researches and writes at the interfaces among medicine, religion, culture, and history. 
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